The Outer Worlds 2 Side Effects Guaranteed Trailer Reveals PS5 Expansion

PlayStation has released a trailer for Side Effects Guaranteed, the first chapter of a two-part expansion for The Outer Worlds 2. The trailer gives PS5 players a look at the new story content, which sends the player and their crew to a derelict ship and a brand-new region.

What the expansion contains

Side Effects Guaranteed begins with a distress signal that draws the player and the crew of the Incognito to an abandoned ship. Aboard, they find the ship's crew in suspended animation, infected with something that causes explosive cell death. The search for a cure leads to Elysium Valley, a new region on the planet Eden.

Two agents of an organization called Sub Rosa have very different plans for the valley, and the player's choices determine the fate of the valley, the crew, and Sub Rosa itself. As the trailer's title suggests, side effects may vary depending on how things play out.

About The Outer Worlds 2

The Outer Worlds 2 is a sci-fi first-person RPG and the sequel to the acclaimed original from Obsidian Entertainment. Players take the role of an Earth Directorate agent investigating devastating rifts that threaten humanity, a search that leads to Arcadia, a colony torn by factional war between the ruling Protectorate and a rebellious religious order. Decisions about strengths, flaws, crew members, and trusted factions shape the outcome for the colony and the galaxy.

The game is available on PS5, having launched on October 29, 2025, and currently costs $22.00 on MegaGame.

With Side Effects Guaranteed now unveiled, PS5 players have a fresh reason to return to The Outer Worlds 2 or a good moment to jump in for the first time. The expansion's branching choices and new region on Eden extend the decision-driven RPG experience the series is known for.

Available on MegaGame: The Outer Worlds 2

Source: PlayStation